|Aiming at discovery of new drugs and elucidation of viral evolution, we investigate the following subjects expanding from chemistry to biology.
- Development of an AIDS eradication strategy using phosphoinositide derivatives.
- Development of anti-fibrosis and anti-cancer metastasis drugs.
- Development of brain-targeting drugs.
- Development of compounds affecting zinc enzymes and signaling proteins.
- Development of anti-virus agents including anti-HIV compounds.
- Function analysis of HIV Vpr/Vpx proteins to elucidate viral evolution paradigm.