Professor | SAKAGAMI Takuro |
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Associate Professor | ICHIYASU Hidenori |
Assistant Professor | YOSHIDA Chieko |
Assistant Professor | SARUWATARI Koichi |
Our aim is to clarify the mechanism of respiratory disease and establish novel treatment, trough translational research. The projects of our research are as follows:
1) Anti-tumor immune response induced by cancer associated fibroblasts (CAF)and development of new immunotherapy for lung adenocarcinoma.
2) Elucidation of the clinical significance and functional analyses of tumorinfiltrating lymphocytes expressing drebrin in lung cancer patients.
3) Development of a new lung cancer therapy targeting gut microbiome.
4) Clinical study on the epidemiology and fibrotic process of interstitial lung abnormality (ILA) detected in a health screening cohort(Kumamoto ILA study in Japan, KILA-J)
5) Study of the relationship between the lung fibrotic process and the gut-lung axis
6) Research to elucidate the pathogenesis of connective tissue disease-related interstitial lung diseases and rare lung diseases and to develop new treatments
7) Elucidation of the mechanism of biologics response to mucus plugs in severe asthma.
8) Research on clinical profile and background factors for achieving clinical remission of severe asthma with biologic therapy.
9) Elucidation of a novel homeostatic mechanism by anti-cytokine anto-antibody analysis.
10) Research on optimization of antibiotic treatment for intractable respiratory infections.
11) Elucidation of the host immune response in disseminated and pulmonary non-tuberculous mycobacterial disease.