

Department of Respiratory Medicine
Great Departments / Basic and Clinical Medicine
| Professor | SAKAGAMI Takuro | 
|---|---|
| Associate Professor | ICHIYASU Hidenori | 
| Assistant Professor | YOSHIDA Chieko | 
| Assistant Professor | SARUWATARI Koichi | 
Our aim is to clarify the mechanism of respiratory disease and establish  novel treatment, trough translational research. The projects of our research  are as follows:
- 1). Anti-tumor immune response induced by cancer associated fibroblasts (CAF) and development of new immunotherapy for lung adenocarcinoma 
- 2). The clinical research for combined cancer immunotherapy with escape of tumor immune suppression and active immunity. 
- 3). The development of treatment for small cell lung cancer by controlling activation of tumor-associated macrophages. 
- 4). Elucidation of the clinical significance and functional analyses of tumor-infiltrating lymphocytes expressing drebrin in lung cancer patients. 
- 5). Development of a novel cancer therapy targeted at gut microbiome in advanced thoracic malignancies. 
- 6). The elucidation of the mechanism of fibrosis in health screening-detected interstitial lung abnormality(ILA). 
- 7). The strategy of appropriate antibiotic use in the treatment of intractable respiratory tract infections. 
- 8). Research on the development of new treatment methods for acute exacerbation of IPF and progressive pulmonary fibrosis (PPF). 
- 9). Novel cytokine function by analysis of autoantibody against certain cytokines, such as GM-CSF and IFN-γ. 
- 10). Elucidation of the host immune response to lung nontuberculous mycobacterial infection. 











