- ホーム
- 講座
- 先端生命医療科学部門
- 脳神経内科学
スタッフ
| 教授 | 植田 光晴 |
|---|---|
| 准教授 | 三隅 洋平 |
研究テーマ
【研究プロジェクト名および概要】
私たちの研究室では、
- アミロイドーシスの病態解析と診断法および治療法開発
- 遺伝性脳小血管病（CADASILなど）の病態解析と診断法の開発
- 脳血管障害の超急性期治療とMRI/CT・神経超音波・脳血管撮影・SPECTを用いた臨床解析
- 神経難病の病態解析
などを行っています。
Figure 1: Therapeutic targets for hereditary transthyretin amyloidosis
Figure 2: LMD-LC-MS/MS for analyzing amyloid deposits.
Figure 3: CADASIL. Typical distribution of white matter lesions (upper). GOM (lower left), and NOTCH3 R133C mutation (lower right).
Our laboratory is engaged in the following research projects:
– Elucidation of the pathological mechanisms of amyloidosis and the development of diagnostic and therapeutic strategies;
– Pathological and genetic analyses of hereditary cerebral small vessel diseases (SVDs), including CADASIL, and the development of diagnostic methodologies;
– Clinical research on thrombolytic therapies in the hyperacute phase of stroke, utilizing MRI, CT, neurosonography, digital subtraction angiography (DSA), and SPECT imaging;
– Investigation of the pathophysiological mechanisms underlying intractable neurological diseases.